CHD4 R975H mutant activates tumorigenic pathways and promotes stemness and M2-like macrophage polarization in endometrial cancer
Author:
Funder
National Natural Science Foundation of China
Research Grants Council of Hong Kong China
Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41598-024-69233-6.pdf
Reference40 articles.
1. Makker, V. et al. Endometrial cancer. Nat. Rev. Dis. Primers 7, 88. https://doi.org/10.1038/s41572-021-00324-8 (2021).
2. Katoh, M. & Katoh, M. WNT signaling and cancer stemness. Essays Biochem. 66, 319–331. https://doi.org/10.1042/EBC20220016 (2022).
3. Munoz-Galvan, S. et al. Downregulation of MYPT1 increases tumor resistance in ovarian cancer by targeting the Hippo pathway and increasing the stemness. Mol. Cancer 19, 7. https://doi.org/10.1186/s12943-020-1130-z (2020).
4. Genin, M., Clement, F., Fattaccioli, A., Raes, M. & Michiels, C. M1 and M2 macrophages derived from THP-1 cells differentially modulate the response of cancer cells to etoposide. BMC Cancer 15, 577. https://doi.org/10.1186/s12885-015-1546-9 (2015).
5. Sun, S. et al. 8-bromo-7-methoxychrysin reversed M2 polarization of tumor-associated macrophages induced by liver cancer stem-like cells. Anticancer Agents Med. Chem. 17, 286–293. https://doi.org/10.2174/1871520616666160204112556 (2017).
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