Touchscreen testing reveals clinically relevant cognitive abnormalities in a mouse model of schizophrenia lacking metabotropic glutamate receptor 5-Reference-Cited by-同舟云学术

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Touchscreen testing reveals clinically relevant cognitive abnormalities in a mouse model of schizophrenia lacking metabotropic glutamate receptor 5

Published:2018-11-06 Issue:1 Volume:8 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Zeleznikow-Johnston Ariel M.,Renoir Thibault,Churilov Leonid,Li Shanshan,Burrows Emma L.,Hannan Anthony J.

Funder

Department of Health | National Health and Medical Research Council

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-018-33929-3.pdf

Reference62 articles.

1. Hoeffer, C. A. & Klann, E. mTOR signaling: At the crossroads of plasticity, memory and disease. Trends Neurosci. 33, 67–75 (2010).

2. Mannaioni, G., Marino, M. J., Valenti, O., Traynelis, S. F. & Conn, P. J. Metabotropic glutamate receptors 1 and 5 differentially regulate CA1 pyramidal cell function. J. Neurosci. 21, 5925–5934 (2001).

3. Thomas, G. M. & Huganir, R. L. MAPK cascade signalling and synaptic plasticity. Nat Rev Neurosci 5, 173–183 (2004).

4. López-Bendito, G. & Shigemoto, R. Fairén, a & Luján, R. Differential distribution of group I metabotropic glutamate receptors during rat cortical development. Cereb. Cortex 12, 625–638 (2002).

5. Lu, Y. M. et al. Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP. J. Neurosci. 17, 5196–5205 (1997).

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