Quantitative Profiling of Oncometabolites in Frozen and Formalin-Fixed Paraffin-Embedded Tissue Specimens by Liquid Chromatography Coupled with Tandem Mass Spectrometry-Reference-Cited by-同舟云学术

Quantitative Profiling of Oncometabolites in Frozen and Formalin-Fixed Paraffin-Embedded Tissue Specimens by Liquid Chromatography Coupled with Tandem Mass Spectrometry

Published:2019-08-02 Issue:1 Volume:9 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Bao Xun,Wu Jianmei,Shuch Brian,LoRusso Patricia,Bindra Ranjit S.^ORCID,Li Jing

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-019-47669-5.pdf

Reference21 articles.

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2. Thompson, C. B. Metabolic enzymes as oncogenes or tumor suppressors. N Engl J Med 360, 813–815, https://doi.org/10.1056/NEJMe0810213 (2009).

3. Ward, P. S. et al. The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. Cancer Cell 17, 225–234, https://doi.org/10.1016/j.ccr.2010.01.020 (2010).

4. Yang, M., Soga, T. & Pollard, P. J. Oncometabolites: linking altered metabolism with cancer. J Clin Invest 123, 3652–3658, https://doi.org/10.1172/JCI67228 (2013).

5. Pollard, P. J. et al. Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations. Hum Mol Genet 14, 2231–2239, https://doi.org/10.1093/hmg/ddi227 (2005).

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