Recombinant production of human α2-macroglobulin variants and interaction studies with recombinant G-related α2-macroglobulin binding protein and latent transforming growth factor-β2-Reference-Cited by-同舟云学术

Recombinant production of human α2-macroglobulin variants and interaction studies with recombinant G-related α2-macroglobulin binding protein and latent transforming growth factor-β2

Published:2019-06-24 Issue:1 Volume:9 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Marino-Puertas Laura,del Amo-Maestro Laura,Taulés Marta,Gomis-Rüth F. Xavier^ORCID,Goulas Theodoros

Funder

Spanish Ministry of Economy, Innovation and Competitivity

Spanish Ministry of Science and Education

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-019-45712-z.pdf

Reference39 articles.

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2. Goulas, T. et al. Structural and functional insight into pan-endopeptidase inhibition by α2-macroglobulins. Biol. Chem. 398, 975–994 (2017).

3. Barrett, A. J. & Starkey, P. M. The interaction of α2-macrolgobulin with proteinases. Biochem. J. 133, 709–724 (1973).

4. Sottrup-Jensen, L., Sand, O., Kristensen, T. & Fey, G. H. The α-macroglobulin bait region. Sequence diversity and localisation of cleavage sites for proteinases in five mammalian α-macroglobulins. J. Biol. Chem. 264, 15781–15789 (1989).

5. Garcia-Ferrer, I. et al. Structural and functional insights into Escherichia coli α2-macroglobulin endopeptidase snap-trap inhibition. Proc. Natl. Acad. Sci. USA 112, 8290–8295 (2015).

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