Utilizing direct and indirect information to improve the COVID-19 vaccination booster scheduling-Reference-Cited by-同舟云学术

Utilizing direct and indirect information to improve the COVID-19 vaccination booster scheduling

Published:2024-04-06 Issue:1 Volume:14 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Dery Yotam,Yechezkel Matan,Ben-Gal Irad,Yamin Dan

Abstract

AbstractCurrent global COVID-19 booster scheduling strategies mainly focus on vaccinating high-risk populations at predetermined intervals. However, these strategies overlook key data: the direct insights into individual immunity levels from active serological testing and the indirect information available either through sample-based sero-surveillance, or vital demographic, location, and epidemiological factors. Our research, employing an age-, risk-, and region-structured mathematical model of disease transmission—based on COVID-19 incidence and vaccination data from Israel between 15 May 2020 and 25 October 2021—reveals that a more comprehensive strategy integrating these elements can significantly reduce COVID-19 hospitalizations without increasing existing booster coverage. Notably, the effective use of indirect information alone can considerably decrease COVID-19 cases and hospitalizations, without the need for additional vaccine doses. This approach may also be applicable in optimizing vaccination strategies for other infectious diseases, including influenza.

Funder

HORIZON EUROPE European Research Council

Koret Foundation

Publisher

Springer Science and Business Media LLC

Link

https://www.nature.com/articles/s41598-024-58690-8.pdf

Reference44 articles.

1. Statement on the fifteenth meeting of the IHR (2005) Emergency Committee on the COVID-19 pandemic. https://www.who.int/news/item/05-05-2023-statement-on-the-fifteenth-meeting-of-the-international-health-regulations-(2005)-emergency-committee-regarding-the-coronavirus-disease-(covid-19)-pandemic?adgroupsurvey={adgroupsurvey}&gclid=Cj0KCQjw4NujBhC5ARIsAF4Iv6eiihrUYTrhg8SzEN5XofqdJfZ0wECz8ykhe5iEfl-8iBkL54VCFw8aAinaEALw_wcB.

2. Underlying Medical Conditions Associated with Higher Risk for Severe COVID-19: Information for Healthcare Professionals | CDC. https://www.cdc.gov/coronavirus/2019-ncov/hcp/clinical-care/underlyingconditions.html.

3. Coronavirus (COVID-19) Update: FDA Authorizes Changes to Simplify Use of Bivalent mRNA COVID-19 Vaccines | FDA. https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-changes-simplify-use-bivalent-mrna-covid-19-vaccines.

4. A guide to the COVID-19 spring booster 2023—GOV.UK. https://www.gov.uk/government/publications/covid-19-vaccination-spring-booster-resources/a-guide-to-the-covid-19-spring-booster-2023.

5. COVID-19 vaccination: A guide to booster vaccination for individuals aged 18 years and over and those aged 16 years and over who are at risk—GOV.UK. https://www.gov.uk/government/publications/covid-19-vaccination-booster-dose-resources/covid-19-vaccination-a-guide-to-booster-vaccination-for-individuals-aged-18-years-and-over.