In vivo measurements reveal a single 5′-intron is sufficient to increase protein expression level in Caenorhabditis elegans-Reference-Cited by-同舟云学术

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In vivo measurements reveal a single 5′-intron is sufficient to increase protein expression level in Caenorhabditis elegans

Published:2019-06-24 Issue:1 Volume:9 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Crane Matthew M.,Sands Bryan,Battaglia Christian,Johnson Brock,Yun Soo,Kaeberlein Matt,Brent Roger,Mendenhall Alex^ORCID

Funder

U.S. Department of Health & Human Services | NIH | National Institute on Aging

U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences

U.S. Department of Health & Human Services | NIH | National Cancer Institute

Pilot Grant from the Nathan Shock Center for Excellence in the Basic Biology of Aging at the University of Washington to AM

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-019-45517-0.pdf

Reference69 articles.

1. Shi, Y. Mechanistic insights into precursor messenger RNA splicing by the spliceosome. Nature reviews. Molecular cell biology 18, 655–670, https://doi.org/10.1038/nrm.2017.86 (2017).

2. Shi, Y. The Spliceosome: A Protein-Directed Metalloribozyme. Journal of molecular biology 429, 2640–2653, https://doi.org/10.1016/j.jmb.2017.07.010 (2017).

3. Jo, B. S. & Choi, S. S. Introns: The Functional Benefits of Introns in Genomes. Genomics Inform 13, 112–118, https://doi.org/10.5808/GI.2015.13.4.112 (2015).

4. Roy, B., Haupt, L. M. & Griffiths, L. R. Review: Alternative Splicing (AS) of Genes As An Approach for Generating Protein Complexity. Current genomics 14, 182–194, https://doi.org/10.2174/1389202911314030004 (2013).

5. Carazo, F., Romero, J. P. & Rubio, A. Upstream analysis of alternative splicing: a review of computational approaches to predict context-dependent splicing factors. Brief Bioinform. https://doi.org/10.1093/bib/bby005 (2018).

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