Understanding non-linear effects from Hill-type dynamics with application to decoding of p53 signaling
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-20466-2.pdf
Reference91 articles.
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2. Levine, J. H., Lin, Y. & Elowitz, M. B. Functional Roles of Pulsing in Genetic Circuits. Science 342, 1193–1200 (2013).
3. Csikász-Nagy, A. & Mura, I. Role of computational modeling in understanding cell cycle oscillators. Methods in Molecular Biology 1342, 59–70 (2016).
4. Purvis, J. E. et al. p53 Dynamics Control Cell Fate. Science 336, 1440–1444 (2012).
5. Goldbeter, A. Computational approaches to cellular rhythms. Nature 420, 238–245 (2002).
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1. A Hill type equation reveals the regulation principle of target protein expression led by p53 pulsing;2023-10-27
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3. A Hill type equation can predict target gene expression driven by p53 pulsing;FEBS Open Bio;2021-05-27
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