A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK-Reference-Cited by-同舟云学术

A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK

Published:2018-02-16 Issue:1 Volume:8 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Chiarelli Laurent R.^ORCID,Mori Giorgia,Orena Beatrice Silvia,Esposito Marta,Lane Thomas,de Jesus Lopes Ribeiro Ana Luisa,Degiacomi Giulia,Zemanová Júlia,Szádocka Sára,Huszár Stanislav,Palčeková Zuzana,Manfredi Marcello,Gosetti Fabio^ORCID,Lelièvre Joël,Ballell Lluis,Kazakova Elena,Makarov Vadim,Marengo Emilio,Mikusova Katarina,Cole Stewart T.,Riccardi Giovanna,Ekins Sean,Pasca Maria Rosalia^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-018-21614-4.pdf

Reference21 articles.

1. Zignol, M. C. Twenty years of global surveillance of antituberculosis-drug resistance. N Engl J Med 375, 1081–1089, https://doi.org/10.1056/NEJMsr1512438 (2016).

2. WHO. Global tuberculosis report. World Health Organization (2016).

3. Fischbach, M. A. Combination therapies for combating antimicrobial resistance. Curr Opin Microbiol 14, 519–523, https://doi.org/10.1016/j.mib.2011.08.003 (2011).

4. Li, K. et al. Multitarget drug discovery for tuberculosis and other infectious diseases. J Med Chem 57, 3126–3139, https://doi.org/10.1021/jm500131s (2014).

5. Oldfield, E. & Feng, X. Resistance-resistant antibiotics. Trends Pharmacol Sci 35, 664–674, https://doi.org/10.1016/j.tips.2014.10.007 (2014).

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