Pilot study with IBAT inhibitor A4250 for the treatment of cholestatic pruritus in primary biliary cholangitis
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-25214-0.pdf
Reference24 articles.
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2. Talwalkar, J. A., Souto, E., Jorgensen, R. A. & Lindor, K. D. Natural history of pruritus in primary biliary cirrhosis. Clin. Gastroenterol. Hepatol. 1, 297–302 (2003).
3. Beuers, U., Kremer, A. E., Bolier, R. & Elferink, R. P. Pruritus in cholestasis: facts and fiction. Hepatology 60, 399–407, https://doi.org/10.1002/hep.26909 (2014).
4. EASL Clinical Practice Guidelines: The diagnosis and management of patients with primary biliary cholangitis. J. Hepatol., https://doi.org/10.1016/j.jhep.2017.03.022 (2017).
5. Nevens, F. et al. A placebo-controlled trial of obeticholic acid in primary biliary cholangitis. N. Engl. J. Med. 375, 631–643, https://doi.org/10.1056/NEJMoa1509840 (2016).
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