Characterization of mouse ocular response to a 35-day spaceflight mission: Evidence of blood-retinal barrier disruption and ocular adaptations-Reference-Cited by-同舟云学术

Characterization of mouse ocular response to a 35-day spaceflight mission: Evidence of blood-retinal barrier disruption and ocular adaptations

Published:2019-06-03 Issue:1 Volume:9 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Mao Xiao W.,Nishiyama Nina C.,Byrum Stephanie D.,Stanbouly Seta,Jones Tamako,Drew Alyson,Sridharan Vijayalakshmi,Boerma Marjan,Tackett Alan J.,Zawieja David,Willey Jeffrey S.,Delp Michael,Pecaut Michael J.

Funder

NASA | Ames Research Center

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-019-44696-0.pdf

Reference47 articles.

1. Mader, T. H. et al. Optic disc edema, globe flattening, choroidal folds, and hyperopic shifts observed in astronauts after long-duration space flight. Ophthalmology. 118, 2058–69 (2011).

2. Lakin, W. D., Stevens, S. A. & Penar, P. L. Modeling intracranial pressures in microgravity: the influence of the blood-brain barrier. Aviat. Space Environ. Med. 78, 932–936 (2007).

3. Smith, S. M. & Zwart, S. R. Spaceflight-related ocular changes: the potential role of genetics, and the potential of B vitamins as a countermeasure. Curr. Opin. Clin. Nutr. Metab. Care 21(6), 481–488 (2018).

4. Mao, X. W. et al. Space Flight Environment Induces Mitochondrial Oxidative Damage in Ocular Tissue. Radiat Res. 180, 340–50 (2013).

5. Mao, X. W. et al. Impact of Spaceflight and Artificial Gravity on the Mouse Retina: Biochemical and Proteomic Analysis. Int. J. Mol.Sci. 19, 2546 (2018).

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