Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis
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Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-01057-z.pdf
Reference48 articles.
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2. Gandhi, N. R. et al. Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis. Lancet Lond. Engl. 375, 1830–1843, doi: 10.1016/S0140-6736(10)60410-2 (2010).
3. World Health Organization. Global Tuberculosis Report 2015 (WHO, 2015).
4. Zhang, Y. The Magic Bullets and Tuberculosis Drug Targets. Annu. Rev. Pharmacol. Toxicol. 45, 529–564, doi: 10.1146/annurev.pharmtox.45.120403.100120 (2005).
5. Mitchison, D. A. The search for new sterilizing anti-tuberculosis drugs. Front. Biosci. J. Virtual Libr. 9, 1059–1072, doi: 10.2741/1293 (2004).
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