On-chip spatiotemporal electrophysiological analysis of human stem cell derived cardiomyocytes enables quantitative assessment of proarrhythmia in drug development

Author:

Asahi Yumiko,Hamada Tomoyo,Hattori Akihiro,Matsuura Kenji,Odaka Masao,Nomura Fumimasa,Kaneko Tomoyuki,Abe Yasuyuki,Takasuna Kiyoshi,Sanbuissho Atsushi,Yasuda KenjiORCID

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Reference69 articles.

1. Gintant, G. An evaluation of hERG current assay performance: Translating preclinical safety studies to clinical QT prolongation. Pharmacol. Ther. 129, 109–119, http://www.sciencedirect.com/science/article/pii/S0163725810001671, https://doi.org/10.1016/J.PHARMTHERA.2010.08.008 , arXiv:1011.1669v3 (2011).

2. Ponti, F. D. et al. Safety of non-antiarrhythmic drugs that prolong the QT interval or induce torsade de pointes: an overview. Drug safety: an international journal of medical toxicology and drug experience 25, 263–286, https://doi.org/10.2165/00002018-200225040-00004 (2002).

3. Giorgi, M., Bolanos, R., Gonzalez, C. & Di Girolamo, G. QT Interval Prolongation: Preclinical and Clinical Testing Arrhythmogenesis in Drugs and Regulatory Implications. Curr. Drug Saf. 5, 54–57, http://www.eurekaselect.com/openurl/content.php?genre=article&issn=1574-8863&volume=5&issue=1&spage=54, https://doi.org/10.2174/157488610789869148 (2010).

4. Ando, H. et al. A new paradigm for drug-induced torsadogenic risk assessment using human iPS cell-derived cardiomyocytes. J. Pharmacol. Toxicol. Methods 84, 111–127, http://www.sciencedirect.com/science/article/pii/S1056871916301952?via{%}3Dihub, http://www.sciencedirect.com/science/article/pii/S1056871916301952 , https://doi.org/10.1016/J.VASCN.2016.12.003 (2017).

5. Kitaguchi, T. et al. CSAHi study: Evaluation of multi-electrode array in combination with human iPS cell-derived cardiomyocytes to predict drug-induced QT prolongation and arrhythmia — Effects of 7 reference compounds at 10 facilities. J. Pharmacol. Toxicol. Methods 78, 93–102, http://www.sciencedirect.com/science/article/pii/S1056871915300083 , https://doi.org/10.1016/J.VASCN.2015.12.002 (2016).

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3