Author:
Tashbayev B.,Garen T.,Palm Ø.,Chen X.,Herlofson B. B.,Young A.,Hove L. H.,Rykke M.,Singh P. B.,Aqrawi L. A.,Utheim Ø. A.,Utheim T. P.,Jensen J. L.
Abstract
AbstractUnderstanding the impact of the disease on quality of life is crucial in patient management. In this cross-sectional study, general and oral health-related quality of life questionnaires, and thorough examinations of oral and ocular dryness were performed in age- and sex-matched patients with primary Sjögren’s syndrome (pSS group), non-Sjögren’s syndrome sicca (non-SS group) and healthy controls. General and oral health-related quality of life were investigated with the 36-Item Short Form Health Survey and the 14-Item Oral Health Impact Profile questionnaires, respectively. Subjective symptoms of xerostomia and ocular dryness were recorded using the Summated Xerostomia Inventory and Ocular Surface Disease Index, respectively. Clinical examinations included evaluation of clinical oral dryness scores, candida counts, unstimulated and stimulated saliva secretory rates, tear osmolarity, tear film break-up time, Schirmer I test and ocular surface staining. Both patient groups had pronounced signs and symptoms of xerostomia and ocular dryness. Even though the non-SS patients had less severe clinical signs than the pSS patients, they demonstrated much poorer general and oral health-related quality of life. In conclusion, non-SS patients require more attention in order to improve their quality of life.
Publisher
Springer Science and Business Media LLC
Reference73 articles.
1. Ramos-Casals, M., Tzioufas, A. G., Stone, J. H., Siso, A. & Bosch, X. Treatment of primary Sjogren syndrome: a systematic review. Jama 304, 452–460 (2010).
2. Lutman, F. C. & Favata, B. V. Keratoconjunctivitis sicca and buccoglossopharyngitis sicca with enlargement of parotid glands; report of two cases of Sjogren’s syndrome, with pathologic study of a lacrimal gland and the parotid glands in one case. Arch. Ophthal 35, 227–240 (1946).
3. Carsons, S. A review and update of Sjogren’s syndrome: manifestations, diagnosis, and treatment. Am. J. Manag. Care 7, S433–443 (2001).
4. Tabbara, K. & Sharara, N. Sjogren’s syndrome: pathogenesis. Eur. J. Ophthalmol. 9, 1–7 (1999).
5. Tabbara, K. F. & Vera-Cristo, C. L. Sjogren syndrome. Curr. Opin. Ophthalmol. 11, 449–454 (2000).
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