Consequences of VHL Loss on Global DNA Methylome-Reference-Cited by-同舟云学术

Consequences of VHL Loss on Global DNA Methylome

Published:2018-02-20 Issue:1 Volume:8 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Robinson Claire M.,Lefebvre Francois,Poon Betty P.,Bousard Aurelie,Fan Xiaojun,Lathrop Mark,Tost Jorg^ORCID,Kim William Y.,Riazalhosseini Yasser^ORCID,Ohh Michael

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-018-21524-5.pdf

Reference37 articles.

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2. Kaelin, W. G. Jr. The von Hippel-Lindau tumor suppressor protein and clear cell renal carcinoma. Clin Cancer Res 13, 680s–684s, https://doi.org/10.1158/1078-0432.CCR-06-1865 (2007).

3. Robinson, C. M. & Ohh, M. The multifaceted von Hippel-Lindau tumour suppressor protein. FEBS Lett 588, 2704–2711, https://doi.org/10.1016/j.febslet.2014.02.026 (2014).

4. Ohh, M. et al. Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein. Nature cell biology 2, 423–427, https://doi.org/10.1038/35017054 (2000).

5. Maxwell, P. H. et al. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 399, 271–275, https://doi.org/10.1038/20459 (1999).

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