Anti-TNFR1 targeting in humanized mice ameliorates disease in a model of multiple sclerosis
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-31957-7.pdf
Reference50 articles.
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3. Kontermann, R. E., Scheurich, P. & Pfizenmaier, K. Antagonists of TNF action: clinical experience and new developments. Expert Opin. Drug Discov. 4, 279–292 (2009).
4. Dendrou, C. A., Fugger, L. & Friese, M. A. Immunopathology of multiple sclerosis. Nat. Rev. Immunol. 15, 545–558 (2015).
5. Hauser, S. L., Doolittle, T. H., Lincoln, R., Brown, R. H. & Dinarello, C. A. Cytokine accumulations in CSF of multiple sclerosis patients: frequent detection of interleukin-1 and tumour necrosis factor but not interkeukin-6. Neurology 40, 1735–1739 (1990).
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