A comparison of peripapillary vessel density between subjects with normal-tension glaucoma and primary open-angle glaucoma with similar extents of glaucomatous damage

Author:

Lee Min-Woo,Yu Hwa-Young,Park Kee-Sup,Jin Sun-Young,Kim Jin-Soo

Abstract

AbstractThe purpose of this study was to identify differences in retinal microvasculature impairments between patients with normal-tension glaucoma (NTG) and those with primary open-angle glaucoma (POAG) with similar extents of structural and visual field damage. Participants with glaucoma-suspect (GS), NTG, POAG, and normal controls were consecutively enrolled. Peripapillary vessel density (VD) and perfusion density (PD) were compared among the groups. Linear regression analyses were performed to identify the relationship between VD, PD and visual field parameters. The VDs of the full areas were 18.3 ± 0.7, 17.3 ± 1.7, 16.5 ± 1.7, and 15.8 ± 2.3 mm−1 in the control, GS, NTG, and POAG groups, respectively (P < 0.001). The VDs of the outer and inner areas and the PDs of all areas also differed significantly among the groups (all P < 0.001). In the NTG group, the VDs of the full, outer, and inner areas were significantly associated with all visual field parameters including the mean deviation (MD), pattern standard deviation (PSD), and visual field index (VFI). In the POAG group, the VDs of the full and inner areas were significantly associated with PSD and VFI but not with MD. In conclusion, with similar degrees of retinal nerve fiber layer thinning and visual field damage in both groups, the POAG group showed a lower peripapillary VD and PD than the NTG group. VD and PD were significantly associated with visual field loss.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3