Abstract
AbstractThis paper presents a study of the response of FRET based DNA aptasensors in the intracellular environment. Herein, we extend previous studies of aptasensors functioning in the extracellular environment to detection of antigens in the intracellular environment. An essential step in this research is the use of a novel means of achieving the endocytosis of aptasensors. Specifically, it is demonstrated that functioning aptasensors are successfully endocytosed by functionalizing the aptasensors with endocytosis—inducing DSS peptides.
Publisher
Springer Science and Business Media LLC
Reference28 articles.
1. Ghosh, S., Datta, D., Chaudhry, S., Dutta, M. & Stroscio, M. A. Rapid detection of tumor necrosis factor-alpha using quantum dot based optical aptasensor. IEEE Trans. Nanobiosci.17, 417–423 (2018).
2. Ghosh, S., Datta, D., Cheema, M., Dutta, M. & Stroscio, M. A. Aptasensor based optical detection of glycated albumin for diabetes mellitus diagnosis. Nanotechnology28, 20 (2017).
3. Brenneman, K. L., Poduri, S., Stroscio, M. A. & Dutta, M. Optical detection of lead (II) ions using DNA-based nanosensor. IEEE Sens. J.13, 1783–1786 (2013).
4. Brenneman, K. L., Sen, B., Stroscio, M. A. & Dutta, M. Aptamer-based optical bionano sensor for mercury (II) ions. In Nanotechnology Materials and Devices Conference (NMDC), 2010 IEEE 221–224 (IEEE, 2010).
5. Wu, T.-C., Biswas, S., Dutta, M. & Stroscio, M. A. Quantum-dot-based aptamer beacon for the detection of potassium ions. IEEE Trans. Nanotechnol.10, 991–995 (2011).
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