Importance of Zinc Transporter 8 Autoantibody in the Diagnosis of Type 1 Diabetes in Latin Americans

Author:

Gomes Karla Fabiana BrasilORCID,Semzezem Cintia,Batista Rodolfo,Fukui Rosa Tsuneshiro,Santos Aritania Sousa,Correia Márcia Regina,Passos-Bueno Maria Rita,Silva Maria Elizabeth Rossi daORCID

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Reference31 articles.

1. Eisenbarth, G.S. & Lafferty, K. Type 1 diabetes: Cellular, Molecular and Clinical Immunology. Avaliable from http://www.uchsc.edu/misc/diabetes/books.html (2015).

2. Naserke, H. E., Ziegler, A. G., Lampasona, V. & Bonifacio, E. Early development and spreading of autoantibodies to epitopes of IA-2 and their association with progression to type 1 diabetes. J Immunol. 161, 6963–6969 (1998).

3. Herold, K. C. et al. Immune Tolerance Network ITN007AI Study Group. Treatment of patients with new onset type 1 diabetes with a single course of anti-CD3 mAb teplizumab preserves insulin production for up to 5 years. Clin Immunol. 132, 166–173 (2009).

4. Wenzlau, J. M. et al. The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes. Proc Natl Acad Sci USA 104, 17040–5 (2007).

5. Achenbach, P. et al. Autoantibodies to zinc transporter 8 and SLC30A8 genotype stratify type 1 diabetes risk. Diabetologia. 52, 1881–1888 (2009).

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