Author:
Naikoo Gowhar A.,Bano Mustri,Arshad Fareeha,Hassan Israr U.,BaOmar Fatima,Alfagih Iman M.,Tambuwala Murtaza M.
Abstract
AbstractThe escalating risk of diabetes and its consequential impact on cardiac, vascular, ocular, renal, and neural systems globally have compelled researchers to devise cost-effective, ultrasensitive, and reliable electrochemical glucose sensors for the early diagnosis of diabetes. Herein, we utilized advanced composite materials based on nanoporous CuO, CuO/Ag, and CuO/Ag/NiO for glucose detection. The crystalline structure and surface morphology of the synthesized materials were ascertained via powder X-ray diffraction (P-XRD), energy dispersive X-ray (EDX) spectroscopy, scanning electron microscopy (SEM) and transmission electron microscopy (TEM) analysis. The electro-catalytic properties of the manufactured electrode materials for glucose electro-oxidation in alkaline conditions were probed using cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques. Notably, the CuO/Ag/NiO electrode material exhibited exceptional performance as a non-enzymatic glucose sensor, displaying a linear range of 0.001–5.50 mM, an ultrahigh sensitivity of 2895.3 μA mM−1 cm−2, and a low detection limit of 0.1 μM. These results suggest that nanoporous CuO/Ag/NiO-based composite materials are a promising candidate for early diagnosis of hyperglycemia and treatment of diabetes. Furthermore, non-enzymatic glucose sensors may pave the way for novel glucometer markets.
Funder
Ministry of Higher Education, Research and Innovation
King Saud University
Publisher
Springer Science and Business Media LLC
Cited by
9 articles.
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