Treatment of chronic hepadnavirus infection in a woodchuck animal model with an inhibitor of protein folding and trafficking

Author:

Block Timothy M.,Lu Xuanyong,Mehta Anand S.,Blumberg Baruch S.,Tennant Bud,Ebling Mathew,Korba Brent,Lansky David M.,Jacob Gary S.,Dwek Raymond A.

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference23 articles.

1. Mehta, A., Lu, X., Block, T.M., Blumberg, B.S. & Dwek, R.A. Hepatitis B virus envelope proteins vary drastically in their sensitivity to glycan processing. Proc. Natl. Acad. Sci. USA 94, 1822–1827 (1997).

2. Lu, X. et al. Aberrant trafficking of hepatitis B virus glycoproteins in cells in which N-glycan processing is inhibited. Proc. Natl. Acad. Sci USA 94, 2380–2385 (1997).

3. Sherker, A. & Marion, P. Hepadnaviruses and hepatocellular carcinoma. Ann Revs. Microb. 45, 475–508 (1991).

4. Tipples, G.A. et al. Mutations in the HBV RNA-dependent DNA polymerase confers resistance to lamivudine in vivo. Hepatology 24, 714–717 (1996).

5. Tennant, B.C. & Gerin, J.L. The woodchuck model of hepatitis B virus infection. In: The Liver: Biology and pathobiology. 3rd edition. Eds. Aries, I.M. et al. Raven press, Publisher (NY, NY) pp. 1455–1466 (1994).

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