Evaluation of 244,000 synthetic sequences reveals design principles to optimize translation in Escherichia coli
Author:
Publisher
Springer Science and Business Media LLC
Subject
Biomedical Engineering,Molecular Medicine,Applied Microbiology and Biotechnology,Bioengineering,Biotechnology
Link
http://www.nature.com/articles/nbt.4238.pdf
Reference76 articles.
1. Li, G.-W., Burkhardt, D., Gross, C. & Weissman, J.S. Quantifying absolute protein synthesis rates reveals principles underlying allocation of cellular resources. Cell 157, 624–635 (2014).
2. Andersson, S.G. & Kurland, C.G. Codon preferences in free-living microorganisms. Microbiol. Rev. 54, 198–210 (1990).
3. Scott, M., Gunderson, C.W., Mateescu, E.M., Zhang, Z. & Hwa, T. Interdependence of cell growth and gene expression: origins and consequences. Science 330, 1099–1102 (2010).
4. Ceroni, F., Algar, R., Stan, G.-B. & Ellis, T. Quantifying cellular capacity identifies gene expression designs with reduced burden. Nat. Methods 12, 415–418 (2015).
5. Frumkin, I. et al. Gene architectures that minimize cost of gene expression. Mol. Cell 65, 142–153 (2017).
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