Categorizing atherosclerotic plaques by gene expression
Author:
Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s44161-022-00174-x.pdf
Reference5 articles.
1. Pasterkamp, G., den Ruijter, H. M. & Giannarelli, C. False utopia of one unifying description of the vulnerable atherosclerotic plaque: a call for recalibration that appreciates the diversity of mechanisms leading to atherosclerotic disease. Arterioscler. Thromb. Vasc. Biol. 42, e86–e95 (2022). A Review that presents the diversity of mechanisms in atherosclerosis.
2. Guinney, J. et al. The consensus molecular subtypes of colorectal cancer. Nat. Med. 21, 1350–1356 (2015). This paper reports colorectal cancer types based on transcriptome data.
3. Pasterkamp, G. et al. Human validation of genes associated with a murine atherosclerotic phenotype. Arterioscler. Thromb. Vasc. Biol. 36, 1240–1246 (2016). This paper challenges the validity and interpretation of mouse models for atherosclerosis.
4. Hartman, R. J. G. et al. Sex-stratified gene regulatory networks reveal female key driver genes of atherosclerosis involved in smooth muscle cell phenotype switching. Circulation 143, 713–726 (2021). This paper shows the importance of having well-balanced (in this case between males and females) cohorts in transcriptome studies.
5. Depuydt, M. A. C. et al. Microanatomy of the human atherosclerotic plaque by single-cell transcriptomics. Circ. Res. 127, 1437–1455 (2020). This paper reports the cell-type repertoire of human atherosclerotic plaques.
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