Alkaline ceramidase 1–mediated platelet ceramide catabolism mitigates vascular inflammation and abdominal aortic aneurysm formation
Author:
Funder
Ministry of Science and Technology of the People’s Republic of China
National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s44161-023-00364-1.pdf
Reference52 articles.
1. Daugherty, A. & Cassis, L. A. Mouse models of abdominal aortic aneurysms. Arterioscler. Thromb. Vasc. Biol. 24, 429–434 (2004).
2. Golledge, J. Abdominal aortic aneurysm: update on pathogenesis and medical treatments. Nat. Rev. Cardiol. 16, 225–242 (2019).
3. van der Meijden, P. E. J. & Heemskerk, J. W. M. Platelet biology and functions: new concepts and clinical perspectives. Nat. Rev. Cardiol. 16, 166–179 (2019).
4. Vorp, D. A., Mandarino, W. A., Webster, M. W. & Gorcsan, J. 3rd Potential influence of intraluminal thrombus on abdominal aortic aneurysm as assessed by a new non-invasive method. Cardiovasc. Surg. 4, 732–739 (1996).
5. Owens, A. P. 3rd et al. Platelet inhibitors reduce rupture in a mouse model of established abdominal aortic aneurysm. Arterioscler. Thromb. Vasc. Biol. 35, 2032–2041 (2015).
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