Whole-genome sequencing uncovers two loci for coronary artery calcification and identifies ARSE as a regulator of vascular calcification
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Published:2023-12-04
Issue:12
Volume:2
Page:1159-1172
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ISSN:2731-0590
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Container-title:Nature Cardiovascular Research
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language:en
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Short-container-title:Nat Cardiovasc Res
Author:
de Vries Paul S.ORCID, Conomos Matthew P.ORCID, Singh Kuldeep, Nicholson Christopher J., Jain Deepti, Hasbani Natalie R., Jiang WanlinORCID, Lee Sujin, Lino Cardenas Christian L.ORCID, Lutz Sharon M., Wong Doris, Guo XiuqingORCID, Yao Jie, Young Erica P.ORCID, Tcheandjieu CatherineORCID, Hilliard Austin T.ORCID, Bis Joshua C.ORCID, Bielak Lawrence F.ORCID, Brown Michael R., Musharoff Shaila, Clarke Shoa L.ORCID, Terry James G., Palmer Nicholette D.ORCID, Yanek Lisa R.ORCID, Xu HuichunORCID, Heard-Costa NancyORCID, Wessel Jennifer, Selvaraj Margaret Sunitha, Li Rebecca H., Sun XiaoORCID, Turner Adam W., Stilp Adrienne M.ORCID, Khan Alyna, Newman Anne B., Rasheed Asif, Freedman Barry I.ORCID, Kral Brian G.ORCID, McHugh Caitlin P., Hodonsky Chani, Saleheen DanishORCID, Herrington David M., Jacobs David R.ORCID, Nickerson Deborah A., Boerwinkle Eric, Wang Fei Fei, Heiss Gerardo, Jun Goo, Kinney Greg L.ORCID, Sigurslid Haakon H., Doddapaneni HarshaVardhanORCID, Hall Ira M.ORCID, Bensenor Isabela M., Broome JaiORCID, Crapo James D., Wilson James G., Smith Jennifer A.ORCID, Blangero JohnORCID, Vargas Jose D., Mosquera Jose Verdezoto, Smith Joshua D., Viaud-Martinez Karine A.ORCID, Ryan Kathleen A.ORCID, Young Kendra A.ORCID, Taylor Kent D., Lange Leslie A., Emery Leslie S., Bittencourt Marcio S., Budoff Matthew J.ORCID, Montasser May E.ORCID, Yu Miao, Mahaney Michael C., Mahamdeh Mohammed S.ORCID, Fornage MyriamORCID, Franceschini NoraORCID, Lotufo Paulo A., Natarajan PradeepORCID, Wong Quenna, Mathias Rasika A.ORCID, Gibbs Richard A., Do RonORCID, Mehran RoxanaORCID, Tracy Russell P.ORCID, Kim Ryan W., Nelson Sarah C.ORCID, Damrauer Scott M.ORCID, Kardia Sharon L. R., Rich Stephen S.ORCID, Fuster Valentin, Napolioni ValerioORCID, Zhao WeiORCID, Tian Wenjie, Yin XianyongORCID, Min Yuan-IORCID, Manning Alisa K., Peloso GinaORCID, Kelly Tanika N., O’Donnell Christopher J.ORCID, Morrison Alanna C.ORCID, Curran Joanne E.ORCID, Zapol Warren M., Bowden Donald W., Becker Lewis C., Correa AdolfoORCID, Mitchell Braxton D.ORCID, Psaty Bruce M.ORCID, Carr John JeffreyORCID, Pereira Alexandre C.ORCID, Assimes Themistocles L.ORCID, Stitziel Nathan O.ORCID, Hokanson John E., Laurie Cecelia A.ORCID, Rotter Jerome I.ORCID, Vasan Ramachandran S.ORCID, Post Wendy S., Peyser Patricia A.ORCID, Miller Clint L.ORCID, Malhotra RajeevORCID
Funder
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute American Heart Association
Publisher
Springer Science and Business Media LLC
Reference79 articles.
1. Kavousi, M. et al. Evaluation of newer risk markers for coronary heart disease risk classification: a cohort study. Ann. Intern. Med. 156, 438–444 (2012). 2. Budoff, M. J. et al. Ten-year association of coronary artery calcium with atherosclerotic cardiovascular disease (ASCVD) events: the multi-ethnic study of atherosclerosis (MESA). Eur. Heart J. 39, 2401–2408 (2018). 3. Greenland, P., Blaha, M. J., Budoff, M. J., Erbel, R. & Watson, K. E. Coronary calcium score and cardiovascular risk. J. Am. Coll. Cardiol. 72, 434–447 (2018). 4. Polonsky, T. S. et al. Coronary artery calcium score and risk classification for coronary heart disease prediction. JAMA 303, 1610–1616 (2010). 5. Shi, X. et al. Calcification in atherosclerotic plaque vulnerability: friend or foe? Front. Physiol. 11, 56 (2020).
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