Warfarin Pharmacogenomics: A big step forward for individualized medicine: enlightened dosing of warfarin
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics(clinical),Genetics
Link
http://www.nature.com/articles/5201945.pdf
Reference9 articles.
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2. Rieder MJ, Reiner AP, Gage BF et al: Effect of VKORC1 Haplotypes on transcriptional regulation and warfarin dose. N Engl J Med 2005; 352: 2285–2293.
3. Kamali F, Khan TI, King BP et al: Contribution of age, body size, and CYP2C9 genotype to anticoagulant response to warfarin. Clin Pharmacol Ther 2004; 75: 204–212.
4. Carlquist JF, Horne BD, Muhlestein JB : Genotypes of the cytochrome p450 isoform, CYP2C9, and the vitamin K epoxide reductase comlex subunit 1 conjointly determine stable warfarin dose: a prospective study. J Thromb Thrombolysis 2006; 22: 191–197.
5. Wadelius M, Chen LY, Eriksson N et al: Association of warfarin dose with genes involved in its action and metabolism. Hum Genet 2007; 121: 23–34.
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