The nociceptin/orphanin FQ receptor: a target with broad therapeutic potential-Reference-Cited by-同舟云学术

The nociceptin/orphanin FQ receptor: a target with broad therapeutic potential

Published:2008-08 Issue:8 Volume:7 Page:694-710
ISSN:1474-1776
Container-title:Nature Reviews Drug Discovery
language:en
Short-container-title:Nat Rev Drug Discov

Author:

Lambert David G.

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology,General Medicine

Link

http://www.nature.com/articles/nrd2572.pdf

Reference234 articles.

1. Meunier, J. C. et al. Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor. Nature 377, 532–535 (1995).

2. Reinscheid, R. K. et al. Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor. Science 270, 792–794 (1995). These two references represent the beginning of the N/OFQ–NOP field. In addition, they are of interest to the general pharmacologist as they are the first example of successful reverse pharmacology (deorphanization).

3. Mogil, J. S. & Pasternak, G. W. The molecular and behavioral pharmacology of the orphanin FQ/nociceptin peptide and receptor family. Pharmacol. Rev. 53, 381–415 (2001).

4. Chiou, L. C. et al. Nociceptin/orphanin FQ peptide receptors: pharmacology and clinical implications. Curr. Drug Targets. 8, 117–135 (2007).

5. Zeilhofer, H. U. & Calo, G. Nociceptin/orphanin FQ and its receptor — potential targets for pain therapy? J. Pharmacol. Exp. Ther. 306, 423–429 (2003).

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