The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein-Reference-Cited by-同舟云学术

The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein

Published:2008-05-18 Issue:6 Volume:10 Page:643-653
ISSN:1465-7392
Container-title:Nature Cell Biology
language:en
Short-container-title:Nat Cell Biol

Author:

Zhao Xudong,Heng Julian Ik-Tsen,Guardavaccaro Daniele,Jiang Richeng,Pagano Michele,Guillemot Francois,Iavarone Antonio,Lasorella Anna

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology

Link

http://www.nature.com/articles/ncb1727.pdf

Reference48 articles.

1. Stanton, B. R., Perkins, A. S., Tessarollo, L., Sassoon, D. A. & Parada, L. F. Loss of N-Myc function results in embryonic lethality and failure of the epithelial component of the embryo to develop. Genes Dev. 6, 2235–2247 (1992).

2. Stanton, B. R. & Parada, L. F. The N-Myc proto-oncogene: developmental expression and in vivo site-directed mutagenesis. Brain Pathol. 2, 71–83 (1992).

3. Knoepfler, P. S., Cheng, P. F. & Eisenman, R. N. N-Myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation. Genes Dev. 16, 2699–2712 (2002).

4. Kenney, A. M., Cole, M. D. & Rowitch, D. H. N-Myc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors. Development 130, 15–28 (2003).

5. Kenney, A. M., Widlund, H. R. & Rowitch, D. H. Hedgehog and PI-3 kinase signaling converge on N-Myc1 to promote cell cycle progression in cerebellar neuronal precursors. Development 131, 217–228 (2004).

Cited by 224 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Novel Genetic Variant in HUWE1;Neurology Genetics;2024-08

2. Suppression of interferon α and γ response by Huwe1-mediated Miz1 degradation promotes SARS-CoV-2 replication;Frontiers in Immunology;2024-07-05

3. Induced degradation of lineage-specific oncoproteins drives the therapeutic vulnerability of small cell lung cancer to PARP inhibitors;Science Advances;2024-01-19

4. Hepatic Huwe1 loss protects mice from non-alcoholic fatty liver disease through lipid metabolic rewiring;iScience;2023-12

5. MBL-1 and EEL-1 affect the splicing and protein levels of MEC-3 to control dendrite complexity;PLOS Genetics;2023-09-20