FOXOs: signalling integrators for homeostasis maintenance
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/nrm3507.pdf
Reference160 articles.
1. van der Horst, A. & Burgering, B. M. Stressing the role of FoxO proteins in lifespan and disease. Nature Rev. Mol. Cell Biol. 8, 440–450 (2007).
2. Dansen, T. B. & Burgering, B. M. Unravelling the tumor-suppressive functions of FOXO proteins. Trends Cell Biol. 18, 421–429 (2008).
3. Kenyon, C. J. The genetics of ageing. Nature 464, 504–512 (2010).
4. Paik, J. H. et al. FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis. Cell 128, 309–323 (2007). The first description of mice with conditional deletion of Foxo1, Foxo3 and Foxo4 . Shows that FOXOs can act as tumour suppressors.
5. Bridge, D. et al. FoxO and stress responses in the cnidarian Hydra vulgaris. PLoS ONE 5, e11686 (2010).
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