Conversion of abiraterone to D4A drives anti-tumour activity in prostate cancer-Reference-Cited by-同舟云学术

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Conversion of abiraterone to D4A drives anti-tumour activity in prostate cancer

Published:2015-06-01 Issue:7560 Volume:523 Page:347-351
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Li Zhenfei,Bishop Andrew C.,Alyamani Mohammad,Garcia Jorge A.,Dreicer Robert,Bunch Dustin,Liu Jiayan,Upadhyay Sunil K.,Auchus Richard J.,Sharifi Nima

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature14406.pdf

Reference26 articles.

1. Titus, M. A., Schell, M. J., Lih, F. B., Tomer, K. B. & Mohler, J. L. Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer. Clin. Cancer Res. 11, 4653–4657 (2005)

2. Montgomery, R. B. et al. Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth. Cancer Res. 68, 4447–4454 (2008)

3. Chang, K. H. et al. A gain-of-function mutation in DHT synthesis in castration-resistant prostate cancer. Cell 154, 1074–1084 (2013)

4. Knudsen, K. E. & Penning, T. M. Partners in crime: deregulation of AR activity and androgen synthesis in prostate cancer. Trends Endocrinol. Metab. 21, 315–324 (2010)

5. Chang, K. H. & Sharifi, N. Prostate cancer-from steroid transformations to clinical translation. Nature Rev. Urol. 9, 721–724 (2012)

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