The genomic landscape of response to EGFR blockade in colorectal cancer-Reference-Cited by-同舟云学术

The genomic landscape of response to EGFR blockade in colorectal cancer

Published:2015-09-30 Issue:7572 Volume:526 Page:263-267
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Bertotti Andrea,Papp Eniko,Jones Siân,Adleff Vilmos,Anagnostou Valsamo,Lupo Barbara,Sausen Mark,Phallen Jillian,Hruban Carolyn A.,Tokheim Collin,Niknafs Noushin,Nesselbush Monica,Lytle Karli,Sassi Francesco,Cottino Francesca,Migliardi Giorgia,Zanella Eugenia R.,Ribero Dario,Russolillo Nadia,Mellano Alfredo,Muratore Andrea,Paraluppi Gianluca,Salizzoni Mauro,Marsoni Silvia,Kragh Michael,Lantto Johan,Cassingena Andrea,Li Qing Kay,Karchin Rachel,Scharpf Robert,Sartore-Bianchi Andrea,Siena Salvatore,Diaz Luis A.,Trusolino Livio,Velculescu Victor E.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature14969.pdf

Reference39 articles.

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2. Diaz, L. A., Jr et al. The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers. Nature 486, 537–540 (2012)

3. Misale, S. et al. Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer. Nature 486, 532–536 (2012)

4. Amado, R. G. et al. Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J. Clin. Oncol. 26, 1626–1634 (2008)

5. De Roock, W. et al. Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis. Lancet Oncol. 11, 753–762 (2010)

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