ASC-J9 ameliorates spinal and bulbar muscular atrophy phenotype via degradation of androgen receptor-Reference-Cited by-同舟云学术

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ASC-J9 ameliorates spinal and bulbar muscular atrophy phenotype via degradation of androgen receptor

Published:2007-03 Issue:3 Volume:13 Page:348-353
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Yang Zhiming,Chang Yu-Jia,Yu I-Chen,Yeh Shuyuan,Wu Cheng-Chia,Miyamoto Hiroshi,Merry Diane E,Sobue Gen,Chen Lu-Min,Chang Shu-Shi,Chang Chawnshang

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm1547.pdf

Reference37 articles.

1. Kennedy, W.R., Alter, M. & Sung, J.H. Progressive proximal spinal and bulbar muscular atrophy of late onset: a sex-linked recessive trait. Neurology 50, 583–593 (1998).

2. La Spada, A.R., Wilson, E.M., Lubahn, D.B., Harding, A.E. & Fischbeck, K.H. Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy. Nature 352, 77–79 (1991).

3. Ringel, S.P., Lava, N.S., Treihaft, M.M., Lubs, M.L. & Lubs, H.A. Late-onset X-linked recessive spinal and bulbar muscular atrophy. Muscle Nerve 1, 297–307 (1978).

4. Sobue, G. et al. X-linked recessive bulbospinal neuronopathy. A clinicopathological study. Brain 112, 209–232 (1989).

5. Katsuno, M. et al. Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy. Neuron 35, 843–854 (2002).

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