TIM3 comes of age as an inhibitory receptor
Author:
Publisher
Springer Science and Business Media LLC
Subject
Energy Engineering and Power Technology,Fuel Technology
Link
http://www.nature.com/articles/s41577-019-0224-6.pdf
Reference159 articles.
1. Monney, L. et al. Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease. Nature 415, 536–541 (2002). This is the first report describing cloning of TIM3 and its definition as an immunoregulatory molecule.
2. McIntire, J. J. et al. Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family. Nat. Immunol. 2, 1109 (2001).
3. Meyers, J. H., Sabatos, C. A., Chakravarti, S. & Kuchroo, V. K. The TIM gene family regulates autoimmune and allergic diseases. Trends Mol. Med. 11, 362–369 (2005).
4. Gao, X. et al. TIM-3 expression characterizes regulatory T cells in tumor tissues and is associated with lung cancer progression. PLOS ONE 7, e30676 (2012).
5. Anderson, A. C. et al. Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells. Science 318, 1141–1143 (2007).
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