Clinical validation of an artificial intelligence-based diabetic retinopathy screening tool for a national health system

Author:

Arenas-Cavalli José TomásORCID,Abarca IgnacioORCID,Rojas-Contreras MaximilianoORCID,Bernuy FernandoORCID,Donoso RodrigoORCID

Abstract

Abstract Objective To evaluate the accuracy and validity of an automated diabetic retinopathy (DR) screening tool (DART, TeleDx, Santiago, Chile) that uses artificial intelligence to analyze ocular fundus photographs for potential implementation in the national Chilean DR screening programme. Method This was an observational study of 1123 diabetic eye exams using a validation protocol designed by the commission of the Chilean Ministry of Health personnel and retina specialists. Results Receiver operating characteristic (ROC) analysis indicated a sensitivity of 94.6% (95% CI: 90.9–96.9%), specificity of 74.3% (95% CI: 73.3–75%), and negative predictive value of 98.1% (95% CI: 96.8–98.9%) for the automated tool at the optimal operating point for DR screening. The area under the ROC curve was 0.915. Conclusions The results of this study suggest that DART is a valid tool that could be implemented in a heterogeneous health network such as the Chilean system.

Publisher

Springer Science and Business Media LLC

Subject

Ophthalmology

Reference39 articles.

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5. Barría F, Martínez F, Verdaguer J. Actualización de la Guía clínica de Retinopatía Diabética para Latinoamérica. Vision. 2020 2016: 1–26.

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