mTORC2 promotes type I insulin-like growth factor receptor and insulin receptor activation through the tyrosine kinase activity of mTOR-Reference-Cited by-同舟云学术

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mTORC2 promotes type I insulin-like growth factor receptor and insulin receptor activation through the tyrosine kinase activity of mTOR

Published:2015-11-20 Issue:1 Volume:26 Page:46-65
ISSN:1001-0602
Container-title:Cell Research
language:en
Short-container-title:Cell Res

Author:

Yin Yancun,Hua Hui,Li Minjing,Liu Shu,Kong Qingbin,Shao Ting,Wang Jiao,Luo Yuanming,Wang Qian,Luo Ting,Jiang Yangfu

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/cr2015133.pdf

Reference44 articles.

1. Kim J, Kundu M, Viollet B, Guan KL . AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat Cell Biol 2011; 13:132–141.

2. Laplante M, Sabatini DM . mTOR signaling in growth control and disease. Cell 2012; 149:274–293.

3. Ben-Sahra I, Howell JJ, Asara JM, Manning BD . Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1. Science 2013; 339:1323–1328.

4. Robitaille AM, Christen S, Shimobayashi M, et al. Quantitative phosphoproteomics reveal mTORC1 activates de novo pyrimidine synthesis. Science 2013; 339:1320–1323.

5. Jacinto E, Loewith R, Schmidt A, et al. Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nat Cell Biol 2004; 6:1122–1128.

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