Genome–wide association studies provide new insights into type 2 diabetes aetiology
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics (clinical),Genetics,Molecular Biology
Link
http://www.nature.com/articles/nrg2178.pdf
Reference33 articles.
1. Neel, J. V. in The Genetics of Diabetes Mellitus (eds Creutzfeldt, W., Kobberling, J. & Neel, J. V.) 1–11 (Springer, Berlin; New York, 1976).
2. O'Rahilly, S., Wainscoat, J. S. & Turner, R. C. Type 2 (non-insulin-dependent) diabetes. New genetics for old nightmares. Diabetologia 31, 407–414 (1988).
3. Horikawa, Y. et al. Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nature Genet. 26, 163–175 (2000).
4. Florez, J. C. et al. Haplotype structure and genotype–phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region. Diabetes 53, 1360–1368 (2004).
5. Gloyn, A. L. et al. Large-scale association studies of variants in genes encoding the pancreatic β-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes. Diabetes 52, 568–572 (2003).
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