Subchronic Rolipram Delivery Activates Hippocampal CREB and Arc, Enhances Retention and Slows Down Extinction of Conditioned Fear
Author:
Publisher
Springer Science and Business Media LLC
Subject
Psychiatry and Mental health,Pharmacology
Link
http://www.nature.com/articles/1300813.pdf
Reference64 articles.
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3. Barad M, Bourtchouladze R, Winder DG, Golan H, Kandel E (1998). Rolipram, a type IV-specific phosphodiesterase inhibitor, facilitates the establishment of long-lasting long-term potentiation and improves memory. Proc Natl Acad Sci USA 95: 15020–15025.
4. Barco A, Pittenger C, Kandel ER (2003). CREB, memory enhancement and the treatment of memory disorders: promises, pitfalls and prospects. Expert Opin Ther Targets 7: 101–114.
5. Bourtchuladze R, Frenguelli B, Blendy J, Cioffi D, Schutz G, Silva AJ (1994). Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein. Cell 79: 59–68.
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