Stat3 as a Therapeutic Target for the Treatment of Psoriasis: A Clinical Feasibility Study with STA-21, a Stat3 Inhibitor-Reference-Cited by-同舟云学术

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Stat3 as a Therapeutic Target for the Treatment of Psoriasis: A Clinical Feasibility Study with STA-21, a Stat3 Inhibitor

Published:2011-01 Issue:1 Volume:131 Page:108-117
ISSN:0022-202X
Container-title:Journal of Investigative Dermatology
language:en
Short-container-title:Journal of Investigative Dermatology

Author:

Miyoshi Ken,Takaishi Mikiro,Nakajima Kimiko,Ikeda Mitsunori,Kanda Takashi,Tarutani Masahito,Iiyama Tatsuo,Asao Naoki,DiGiovanni John,Sano Shigetoshi

Publisher

Elsevier BV

Subject

Cell Biology,Dermatology,Molecular Biology,Biochemistry

Reference39 articles.

1. Interleukin 20: discovery, receptor identification, and role in epidermal function;Blumberg;Cell,2001

2. IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes;Boniface;J Immunol,2005

3. Oncostatin M secreted by skin infiltrating T lymphocytes is a potent keratinocyte activator involved in skin inflammation;Boniface;J Immunol,2007

4. Forced expression of a constitutively active form of Stat3 in mouse epidermis enhances malignant progression of skin tumors induced by two-stage carcinogenesis;Chan;Oncogene,2008

5. Signal transduction pathways and transcriptional regulation in the control of Th17 differentiation;Chen;Semin Immunol,2007

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1. STATs, promising targets for the treatment of autoimmune and inflammatory diseases;European Journal of Medicinal Chemistry;2024-11

2. Synthesis and biological evaluation of novel isoxazoloquinone derivatives as potent STAT3-targeting antipsoriasis agents;Bioorganic Chemistry;2024-10

3. Discovery of novel chrysin derivatives as potential Anti-Psoriasis agents;Bioorganic Chemistry;2024-09

4. Design, Synthesis, and Biological Activity of Novel Quinone Derivatives as Potent STAT3 Inhibitors for Psoriasis Treatment;Journal of Medicinal Chemistry;2024-08-16

5. A human STAT3 gain-of-function variant drives local Th17 dysregulation and skin inflammation in mice;Journal of Experimental Medicine;2024-06-11

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