Genome-scale metabolic modelling of hepatocytes reveals serine deficiency in patients with non-alcoholic fatty liver disease-Reference-Cited by-同舟云学术

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Genome-scale metabolic modelling of hepatocytes reveals serine deficiency in patients with non-alcoholic fatty liver disease

Published:2014-01-14 Issue:1 Volume:5 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Mardinoglu Adil,Agren Rasmus,Kampf Caroline,Asplund Anna,Uhlen Mathias,Nielsen Jens

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/ncomms4083.pdf

Reference66 articles.

1. Gille, C. et al. HepatoNet1: a comprehensive metabolic reconstruction of the human hepatocyte for the analysis of liver physiology. Mol. Syst. Biol. 6, 411 (2010).

2. Baffy, G., Brunt, E. M. & Caldwell, S. H. Hepatocellular carcinoma in non-alcoholic fatty liver disease: an emerging menace. J. Hepatol. 56, 1384–1391 (2012).

3. Neuschwander-Tetri, B. A. & Caldwell, S. H. Nonalcoholic steatohepatitis: summary of an AASLD single topic conference. Hepatology 37, 1202–1219 (2003).

4. Bedogni, G., Kahn, H. S., Bellentani, S. & Tiribelli, C. A simple index of lipid overaccumulation is a good marker of liver steatosis. BMC Gastroenterol. 10, 98 (2010).

5. Lanpher, B., Brunetti-Pierri, N. & Lee, B. Inborn errors of metabolism: the flux from Mendelian to complex diseases. Nat. Rev. Genet. 7, 449–460 (2006).

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