One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs-Reference-Cited by-全球学者库

One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs

Published:2017-06-06 Issue:7 Volume:27 Page:933-945
ISSN:1001-0602
Container-title:Cell Research
language:en
Short-container-title:Cell Res

Author:

Zuo Erwei,Cai Yi-Jun,Li Kui,Wei Yu,Wang Bang-An,Sun Yidi,Liu Zhen,Liu Jiwei,Hu Xinde,Wei Wei,Huo Xiaona,Shi Linyu,Tang Cheng,Liang Dan,Wang Yan,Nie Yan-Hong,Zhang Chen-Chen,Yao Xuan,Wang Xing,Zhou Changyang,Ying Wenqin,Wang Qifang,Chen Ren-Chao,Shen Qi,Xu Guo-Liang,Li Jinsong,Sun Qiang,Xiong Zhi-Qi,Yang Hui

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/cr201781.pdf

Reference37 articles.

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2. Niu Y, Shen B, Cui Y, et al. Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos. Cell 2014; 156:836–843.

3. Yen ST, Zhang M, Deng JM, et al. Somatic mosaicism and allele complexity induced by CRISPR/Cas9 RNA injections in mouse zygotes. Dev Biol 2014; 393:3–9.

4. Izpisua Belmonte JC, Callaway EM, Caddick SJ, et al. Brains, genes, and primates. Neuron 2015; 86:617–631.

5. Jennings CG, Landman R, Zhou Y, et al. Opportunities and challenges in modeling human brain disorders in transgenic primates. Nat Neurosci 2016; 19:1123–1130.

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