CYP3A5 genotype did not impact on nifedipine disposition in healthy volunteers

Author:

Fukuda T,Onishi S,Fukuen S,Ikenaga Y,Ohno M,Hoshino K,Matsumoto K,Maihara A,Momiyama K,Ito T,Fujio Y,Azuma J

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology,Genetics,Molecular Medicine

Reference29 articles.

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2. Shimada T, Yamazaki H, Mimura M, Inui Y, Guengerich FP . Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J Pharmacol Exp Ther 1994; 270: 414–423.

3. Kuehl P, Zhang J, Lin Y, Lamba J, Assem M, Schuetz J et al. Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. Nat Genet 2001; 27: 383–391.

4. Chou FC, Tzeng SJ, Huang JD . Genetic polymorphism of cytochrome P450 3A5 in Chinese. Drug Metab Dispos 2001; 29: 1205–1209.

5. Hustert E, Haberl M, Burk O, Wolbold R, He YQ, Klein K et al. The genetic determinants of the CYP3A5 polymorphism. Pharmacogenetics 2001; 11: 773–779.

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