From sewer to saviour — targeting the lymphatic system to promote drug exposure and activity-Reference-Cited by-同舟云学术

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From sewer to saviour — targeting the lymphatic system to promote drug exposure and activity

Published:2015-10-16 Issue:11 Volume:14 Page:781-803
ISSN:1474-1776
Container-title:Nature Reviews Drug Discovery
language:en
Short-container-title:Nat Rev Drug Discov

Author:

Trevaskis Natalie L.,Kaminskas Lisa M.,Porter Christopher J. H.

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology,General Medicine

Link

http://www.nature.com/articles/nrd4608.pdf

Reference280 articles.

1. Girard, J. P., Moussion, C. & Forster, R. HEVs, lymphatics and homeostatic immune cell trafficking in lymph nodes. Nat. Rev. Immunol. 12, 762–773 (2012).

2. Randolph, G. J. & Miller, N. E. Lymphatic transport of high-density lipoproteins and chylomicrons. J. Clin. Invest. 124, 929–935 (2014).

3. Miller, N. E. et al. Secretion of adipokines by human adipose tissue in vivo: partitioning between capillary and lymphatic transport. Am. J. Physiol. Endocrinol. Metab. 301, E659–E667 (2011).

4. Wiig, H. & Swartz, M. A. Interstitial fluid and lymph formation and transport: physiological regulation and roles in inflammation and cancer. Physiol. Rev. 92, 1005–1060 (2012).

5. Starling, E. H. On the absorption of fluids from the connective tissue spaces. J. Physiol. 19, 312–326 (1896).

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