Targeting monoamine oxidase to dampen NLRP3 inflammasome activation in inflammation
Author:
Publisher
Springer Science and Business Media LLC
Subject
Infectious Diseases,Immunology,Immunology and Allergy
Link
http://www.nature.com/articles/s41423-020-0441-8.pdf
Reference10 articles.
1. Swanson, K. V. et al. The NLRP3 inflammasome: molecular activation and regulation to therapeutics. Nat. Rev. Immunol. 19, 477–489 (2019).
2. Zhou, R. et al. A role for mitochondria in NLRP3 inflammasome activation. Nature 469, 221–225 (2011).
3. Zhong, Z. et al. NF-κB restricts inflammasome activation via elimination of damaged mitochondria. Cell 164, 896–910 (2016).
4. Afonina, I. S. et al. Limiting inflammation - The negative regulation of NF-κB and the NLRP3 inflammasome. Nat. Immunol. 18, 861–869 (2017).
5. Van Bruggen, R. et al. Human NLRP3 inflammasome activation is Nox1-4 independent. Blood 115, 5398–5400 (2010).
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