Distinct editing functions of natural HLA-DM allotypes impact antigen presentation and CD4+ T cell activation
Author:
Funder
Deutsche Forschungsgemeinschaft
Publisher
Springer Science and Business Media LLC
Subject
Infectious Diseases,Immunology,Immunology and Allergy
Link
http://www.nature.com/articles/s41423-018-0181-1.pdf
Reference56 articles.
1. Blum, J. S., Wearsch, P. A. & Cresswell, P. Pathways of antigen processing. Annu. Rev. Immunol. 31, 443–473 (2013).
2. Mellins, E. et al. Defective processing and presentation of exogenous antigens in mutants with normal HLA class II genes. Nature 343, 71–74 (1990).
3. Sloan, V. S. et al. Mediation by HLA-DM of dissociation of peptides from HLA-DR. Nature 375, 802–806 (1995).
4. Grotenbreg, G. M. et al. Empty class II major histocompatibility complex created by peptide photolysis establishes the role of DM in peptide association. J. Biol. Chem. 282, 21425–21436 (2007).
5. Wieczorek, M. et al. MHC class II complexes sample intermediate states along the peptide exchange pathway. Nat. Commun. 7, 13224 (2016).
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