The membrane-associated ubiquitin ligases MARCH2 and MARCH3 target IL-5 receptor alpha to negatively regulate eosinophilic airway inflammation-Reference-Cited by-同舟云学术

The membrane-associated ubiquitin ligases MARCH2 and MARCH3 target IL-5 receptor alpha to negatively regulate eosinophilic airway inflammation

Published:2022-08-19 Issue:10 Volume:19 Page:1117-1129
ISSN:2042-0226
Container-title:Cellular & Molecular Immunology
language:en
Short-container-title:Cell Mol Immunol

Author:

Zeng Lin-Wen,Feng Lu,Liu Rui,Lin Heng,Shu Hong-Bing^ORCID,Li Shu^ORCID

Funder

National Natural Science Foundation of China the CAMS Innovation Fund for Medical Sciences the Fundamental Research Funds for the Central Universities.

the National Key R&D Program of China, National Natural Science Foundation of China and the CAMS Innovation Fund for Medical Sciences

Publisher

Springer Science and Business Media LLC

Subject

Infectious Diseases,Immunology,Immunology and Allergy

Link

https://www.nature.com/articles/s41423-022-00907-9.pdf

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3. Wu D, Molofsky AB, Liang HE, Ricardo-Gonzalez RR, Jouihan HA, Bando JK, et al. Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis. Science. 2011;332:243–7.

4. Hammad H, Lambrecht BN. The basic immunology of asthma. Cell. 2021;184:1469–85.

5. FitzGerald JM, Bleecker ER, Nair P, Korn S, Ohta K, Lommatzsch M, et al. Benralizumab, an anti-interleukin-5 receptor alpha monoclonal antibody, as add-on treatment for patients with severe, uncontrolled, eosinophilic asthma (CALIMA): a randomised, double-blind, placebo-controlled phase 3 trial. Lancet. 2016;388:2128–41.

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