Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease
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Published:2016-12-19
Issue:2
Volume:49
Page:269-273
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ISSN:1061-4036
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Container-title:Nature Genetics
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language:en
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Short-container-title:Nat Genet
Author:
Ji Sun-GouORCID, , Juran Brian D, Mucha Sören, Folseraas Trine, Jostins Luke, Melum Espen, Kumasaka Natsuhiko, Atkinson Elizabeth J, Schlicht Erik M, Liu Jimmy Z, Shah Tejas, Gutierrez-Achury Javier, Boberg Kirsten M, Bergquist Annika, Vermeire Severine, Eksteen Bertus, Durie Peter R, Farkkila Martti, Müller Tobias, Schramm Christoph, Sterneck Martina, Weismüller Tobias J, Gotthardt Daniel N, Ellinghaus David, Braun Felix, Teufel Andreas, Laudes Mattias, Lieb Wolfgang, Jacobs Gunnar, Beuers Ulrich, Weersma Rinse K, Wijmenga Cisca, Marschall Hanns-Ulrich, Milkiewicz Piotr, Pares AlbertORCID, Kontula Kimmo, Chazouillères Olivier, Invernizzi Pietro, Goode Elizabeth, Spiess Kelly, Moore Carmel, Sambrook Jennifer, Ouwehand Willem H, Roberts David J, Danesh John, Floreani Annarosa, Gulamhusein Aliya F, Eaton John E, Schreiber Stefan, Coltescu Catalina, Bowlus Christopher L, Luketic Velimir A, Odin Joseph A, Chopra Kapil B, Kowdley Kris V, Chalasani Naga, Manns Michael P, Srivastava Brijesh, Mells George, Sandford Richard N, Alexander Graeme, Gaffney Daniel J, Chapman Roger W, Hirschfield Gideon M, de Andrade Mariza, Rushbrook Simon M, Franke Andre, Karlsen Tom H, Lazaridis Konstantinos N, Anderson Carl A, ,
Publisher
Springer Science and Business Media LLC
Reference51 articles.
1. Boonstra, K. et al. Primary sclerosing cholangitis is associated with a distinct phenotype of inflammatory bowel disease. Inflamm. Bowel Dis. 18, 2270–2276 (2012). 2. Tischendorf, J.J.W., Hecker, H., Krüger, M., Manns, M.P. & Meier, P.N. Characterization, outcome, and prognosis in 273 patients with primary sclerosing cholangitis: a single center study. Am. J. Gastroenterol. 102, 107–114 (2007). 3. Karlsen, T.H. & Kaser, A. Deciphering the genetic predisposition to primary sclerosing cholangitis. Semin. Liver Dis. 31, 188–207 (2011). 4. Karlsen, T.H., Schrumpf, E. & Boberg, K.M. Update on primary sclerosing cholangitis. Dig. Liver Dis. 42, 390–400 (2010). 5. Bergquist, A. et al. Increased risk of primary sclerosing cholangitis and ulcerative colitis in first-degree relatives of patients with primary sclerosing cholangitis. Clin. Gastroenterol. Hepatol. 6, 939–943 (2008).
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