The nitrate–nitrite–nitric oxide pathway in physiology and therapeutics
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.nature.com/articles/nrd2466.pdf
Reference136 articles.
1. Tannenbaum, S. R. & Correa, P. Nitrate and gastric cancer risks. Nature 317, 675–676 (1985).
2. Mensinga, T. T., Speijers, G. J. & Meulenbelt, J. Health implications of exposure to environmental nitrogenous compounds. Toxicol. Rev. 22, 41–51 (2003).
3. Benjamin, N. et al. Stomach NO synthesis. Nature 368, 502 (1994). The first suggestion of NOS-independent NO generation from inorganic nitrite and in vitro demonstration of its role in gastric host defence.
4. Lundberg, J. O., Weitzberg, E., Lundberg, J. M. & Alving, K. Intragastric nitric oxide production in humans: measurements in expelled air. Gut 35, 1543–1546 (1994). The first demonstration of NOS-independent NO generation from inorganic nitrate and nitrite in humans.
5. Zweier, J. L., Wang, P., Samouilov, A. & Kuppusamy, P. Enzyme-independent formation of nitric oxide in biological tissues. Nature Med. 1, 804–809 (1995). The first report demonstrating NOS-independent NO generation from nitrite in ischaemic heart tissue.
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