Optimization of humanized IgGs in glycoengineered Pichia pastoris-Reference-Cited by-同舟云学术

Optimization of humanized IgGs in glycoengineered Pichia pastoris

Published:2006-01-22 Issue:2 Volume:24 Page:210-215
ISSN:1087-0156
Container-title:Nature Biotechnology
language:en
Short-container-title:Nat Biotechnol

Author:

Li Huijuan,Sethuraman Natarajan,Stadheim Terrance A,Zha Dongxing,Prinz Bianka,Ballew Nicole,Bobrowicz Piotr,Choi Byung-Kwon,Cook W James,Cukan Michael,Houston-Cummings Nga Rewa,Davidson Robert,Gong Bing,Hamilton Stephen R,Hoopes Jack P,Jiang Youwei,Kim Nam,Mansfield Renee,Nett Juergen H,Rios Sandra,Strawbridge Rendall,Wildt Stefan,Gerngross Tillman U

Publisher

Springer Science and Business Media LLC

Subject

Biomedical Engineering,Molecular Medicine,Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

http://www.nature.com/articles/nbt1178.pdf

Reference18 articles.

1. Weiner, L.M. & Carter, P. Tunable antibodies. Nat. Biotechnol. 23, 556–557 (2005).

2. Rothman, R.J., Perussia, B., Herlyn, D. & Warren, L. Antibody-dependent cytotoxicity mediated by natural killer cells is enhanced by castanospermine-induced alterations of IgG glycosylation. Mol. Immunol. 26, 1113–1123 (1989).

3. Lifely, M.R., Hale, C., Boyce, S., Keen, M.J. & Phillips, J. Glycosylation and biological activity of CAMPATH-1H expressed in different cell lines and grown under different culture conditions. Glycobiology 5, 813–822 (1995).

4. Umaña, P. et al. Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibody-dependent cellular cytotoxic activity. Nat. Biotechnol. 17, 176–180 (1999).

5. Shields, R.L. et al. Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human FcγRIII and antibody-dependent cellular toxicity. J. Biol. Chem. 277, 26733–26740 (2002).

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