GLIA: A novel drug discovery target for clinical pain
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.nature.com/articles/nrd1251.pdf
Reference134 articles.
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2. McQuay, H. J. et al. A systematic review of antidepressants in neuropathic pain. Pain 68, 217–227 (1996).
3. Watkins, L. R. & Maier, S. F. Beyond neurons: Evidence that immune and glial cells contribute to pathological pain states. Physiol. Rev. 82, 981–1011 (2002). This article reviews the immunology of peripheral nerves, dorsal root ganglia and spinal nerves; the evidence from animal models of immune involvement in pathological pain; and the evidence that diverse human clinical pain syndromes involve an immune component.
4. Woolf, C. J. & Salter, M. W. Neuronal plasticity: increasing the gain in pain. Science 288, 1765–1769 (2000). An excellent review of neuronal changes implicated in creation and maintenance of exaggerated pain states.
5. Pekny, M. in Progress in Brain Research: Glial Cell Funtion (eds Castellano-Lopez, B. & Nieto-Sampedro, M.) 23–30 (Elsevier, Amsterdam, 2001).
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