Pim-1 regulates cardiomyocyte survival downstream of Akt-Reference-Cited by-同舟云学术

Pim-1 regulates cardiomyocyte survival downstream of Akt

Published:2007-11-25 Issue:12 Volume:13 Page:1467-1475
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Muraski John A,Rota Marcello,Misao Yu,Fransioli Jenna,Cottage Christopher,Gude Natalie,Esposito Grazia,Delucchi Francesca,Arcarese Michael,Alvarez Roberto,Siddiqi Sailay,Emmanuel Gregory N,Wu Weitao,Fischer Kimberlee,Martindale Joshua J,Glembotski Christopher C,Leri Annarosa,Kajstura Jan,Magnuson Nancy,Berns Anton,Beretta Remus M,Houser Steven R,Schaefer Erik M,Anversa Piero,Sussman Mark A

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm1671.pdf

Reference50 articles.

1. Wang, Z. et al. Pim-1: a serine/threonine kinase with a role in cell survival, proliferation, differentiation and tumorigenesis. J. Vet. Sci. 2, 167–179 (2001).

2. Bachmann, M. & Moroy, T. The serine/threonine kinase Pim-1. Int. J. Biochem. Cell Biol. 37, 726–730 (2005).

3. Aho, T.L. et al. Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site. FEBS Lett. 571, 43–49 (2004).

4. Hammerman, P.S., Fox, C.J., Birnbaum, M.J. & Thompson, C.B. Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival. Blood 105, 4477–4483 (2005).

5. Pekarsky, Y. et al. Tcl1 enhances Akt kinase activity and mediates its nuclear translocation. Proc. Natl. Acad. Sci. USA 97, 3028–3033 (2000).

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