Toward precision medicine in pediatric population using cytochrome P450 phenotyping approaches and physiologically based pharmacokinetic modeling-Reference-Cited by-同舟云学术

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Toward precision medicine in pediatric population using cytochrome P450 phenotyping approaches and physiologically based pharmacokinetic modeling

Published:2019-10-10 Issue:3 Volume:87 Page:441-449
ISSN:0031-3998
Container-title:Pediatric Research
language:en
Short-container-title:Pediatr Res

Author:

Magliocco Gaëlle,Rodieux Frédérique,Desmeules Jules,Samer Caroline Flora,Daali Youssef

Publisher

Springer Science and Business Media LLC

Subject

Pediatrics, Perinatology, and Child Health

Link

http://www.nature.com/articles/s41390-019-0609-z.pdf

Reference86 articles.

1. Kearns, G. L. et al. Developmental pharmacology—drug disposition, action, and therapy in infants and children. N. Engl. J. Med. 349, 1157–1167 (2003).

2. van den Anker, J., Reed, M. D., Allegaert, K. & Kearns, G. L. Developmental changes in pharmacokinetics and pharmacodynamics. J. Clin. Pharm. 58, S10–S25 (2018).

3. Allegaert, K. & van den Anker, J. N. Clinical pharmacology in neonates: small size, huge variability. Neonatology 105, 344–349 (2014).

4. Smits, A., Kulo, A., de Hoon, J. N. & Allegaert, K. Pharmacokinetics of drugs in neonates: pattern recognition beyond compound specific observations. Curr. Pharm. Des. 18, 3119–3146 (2012).

5. Nicolas, J., Bouzom, F., Hugues, C. & Ungell, A. Oral drug absorption in pediatrics: the intestinal wall, its developmental changes and current tools for predictions. Biopharm. Drug Dispos. 38, 209–230 (2017).

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